處在變革中的醫用金屬材料

處在變革中的醫用金屬材料Revolutionizing Metallic Biomaterials

進入21世紀,醫用金屬材料正在發生變革。以可降解金屬、納米晶金屬、大塊非晶合金為代表的新型醫用金屬材料被嘗試作為植入材料,材料屬性正在從生物惰性向生物活性和生物功能化(抗菌、抗增生、抗腫瘤)方向發展,同時3D打印技術和薄膜技術也在被嘗試用于金屬植入器械的先進制造以及智能化。本文綜合評述了處于變革中的醫用金屬材料研究現狀,展望了新型醫用金屬材料功能化、復合化、智能化的未來發展趨勢。

Entering 21st century, the metallic biomaterials are revolutionizing. New kinds of metallic biomaterials represented by biodegradable metals, nacocrystalline metals and alloys, and bulk metallic glasses, had been explored as implantable biomaterials, and correspondingly the nature of metallic biomaterials are shifting from the bio-inert (with stainless steel, Co-based alloys and Ti alloys) to bio-active and multi-biofunctional (anti-bacterial, anti-proliferation, anti-cancer, etc.). The newly-emerging 3D printing technology and thin film technology had been applied to the advancing manufacture and intelligence of the medical devices made of metallic biomaterials. In this paper, the current research status of the revolutionizing metallic biomaterials had been reviewed, and the future research and development tendencies for newly-developed metallic biomaterials towards bio-functionalization, composite and intelligence are also proposed.

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